PUBLICATIONS

Catapano, L.A. , Magavi, S.S., Macklis, J.D. 2008. "Neuroanatomical tracing of neuronal projections with Fluoro-Gold." Methods Mol. Biol. 438:353-9.

Magavi, S.S., Macklis, J.D. 2008. "Immunocytochemical analysis of neuronal differentiation." Methods Mol. Biol. 438:345-52.

Magavi, S.S., Macklis, J.D. 2008. "Identification of newborn cells by BrdU labeling and immunocytochemistry in vivo." Methods Mol. Biol. 438:335-43.

Lai, T.*, Jabaudon, D.*, Molyneaux, B.J.‡, Azim, E.‡, Arlotta, P., Menezes, J.R.L., Macklis, J.D. 2008. "SOX5 Controls the Sequential Generation of Distinct Corticofugal Neuron Subtypes." Neuron 57: 232-247. (*equally contributing first authors, ‡equally contributing second authors). pdf

Arlotta, P.*, Molyneaux, B.J.*, Jabaudon, D., Yoshida, Y., Macklis, J.D. 2008. "Ctip2 Controls the Differentiation of Medium Spiny Neurons and the Establishment of the Cellular Architecture of the Striatum." J. Neurosci 28(3): 622-632. (*equally contributing first authors). pdf

Breunig, J.J. , Arellano, J.I., Macklis, J.D., Rakic, P. 2007. "Everything that glitters isn't gold: a critical review of postnatal neural precursor analyses." Cell Stem Cell. 1(6):612-27.

Gao, X., Arlotta, P., Macklis, J.D., Chen, J. 2007. "Conditional knock-out of beta-catenin in postnatal-born dentate gyrus granule neurons results in dendritic malformation." J. Neurosci. 27(52):14317-25.

Molyneaux, B.J.*, Arlotta, P.*, Menezes, J.R.L., Macklis, J.D. 2007. "Neuronal subtype specification in the cerebral cortex." Nat. Rev. Neurosci. 8(6): 427-37. (*equally contributing first authors). pdf

Emsley, J.G., Macklis, J.D. 2006. "Astroglial heterogeneity closely reflects the neuronal-defined anatomy of the adult murine CNS." Neuron Glia Biol. 2(3):175-86.

Özdinler, PH, Macklis, JD (2006) IGF-I specifically enhances axon outgrowth of corticospinal motor neurons. Nat. Neurosci.(11):1371-81. pdf

Sohur, U.S.*, Emsley, J.G.*, Mitchell, B.D., Kempermann, G., and Macklis, J.D. (2006) Adult neurogenesis and cellular brain repair with neural progenitors, precursors, and stem cells. In “The regenerating brain: a recapitulation of development?” Editors: G. Cook, J. Fawcett, R. Keynes, and M. Tessier-Lavigne Special Issue of Philosophical Transactions of the Royal Society (B) 361: 1477-1497. (*equal contribution).

Steele, AD*, Emsley, JG*, Özdinler, PH, Lindquist, S‡, Macklis, JD‡
Prion protein (PrPc) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis.
PNAS. 2006 Feb 28;103(9):3416-21. (*equal contribution, ‡co-senior author). pdf

Magavi, SS, Mitchell, BD, Szentirmai, O, Carter, BS, Macklis, JD
Adult-born and preexisting olfactory granule neurons undergo distinct experience-dependent modifications of their olfacotory responses. J. Neurosci. 2005 Nov 16;25(46):10729-39. pdf

Molyneaux BJ*, Arlotta P*, Hirata T, Hibi M, Macklis JD
Fezl is required for the birth and specification of corticospinal motor neurons.
Neuron. 2005 Sep 15;47(6):817-31. (*equal contribution). pdf

Kishi N, Macklis JD
Dissecting MECP2 function in the central nervous system.
J Child Neurol. 2005 Sep;20(9):753-9.

Arlotta P, Macklis JD
Archeo-cell biology: carbon dating is not just for pots and dinosaurs.
Cell. 2005 Jul 15;122(1):4-6.

Emsley JG, Mitchell BD, Kempermann G, Macklis JD
Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells.
Prog Neurobiol. 2005 Apr;75(5):321-41.

Emsley JG, Mitchell BD, Magavi SS, Arlotta P, Macklis JD
Free in PMC The repair of complex neuronal circuitry by transplanted and endogenous precursors.
NeuroRx. 2004 Oct;1(4):452-71.

Arlotta P*, Molyneaux BJ*, Chen J, Inoue J, Kominami R, Macklis JD
Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo.
Neuron. 2005 Jan 20;45(2):207-21. (*equal contribution). pdf

Mitchell BD, Macklis JD
Large-scale maintenance of dual projections by callosal and frontal cortical projection neurons in adult mice.
J Comp Neurol. 2005 Jan 31;482(1):17-32.

Chen J, Magavi SS, Macklis JD
Neurogenesis of corticospinal motor neurons extending spinal projections in adult mice.
Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16357-62. pdf

Kishi N, Macklis JD
MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions.
Mol Cell Neurosci. 2004 Nov;27(3):306-21.

Catapano LA, Arlotta P, Cage TA, Macklis JD
Stage-specific and opposing roles of BDNF, NT-3 and bFGF in differentiation of purified callosal projection neurons toward cellular repair of complex circuitry.
Eur J Neurosci. 2004 May;19(9):2421-34.
 
Emsley JG*, Arlotta P*, Macklis JD
Star-cross'd neurons: astroglial effects on neural repair in the adult mammalian CNS.
Trends Neurosci. 2004 May;27(5):238-40. (*equal contribution).

Mitchell BD, Emsley JG, Magavi SS, Arlotta P, Macklis JD
Constitutive and induced neurogenesis in the adult mammalian brain: manipulation of endogenous precursors toward CNS repair.
Dev Neurosci. 2004 Mar-Aug;26(2-4):101-17.

Mellough CB, Cui Q, Spalding KL, Symons NA, Pollett MA, Snyder EY, Macklis JD, Harvey AR
Fate of multipotent neural precursor cells transplanted into mouse retina selectively depleted of retinal ganglion cells.
Exp Neurol. 2004 Mar;186(1):6-19.

Eyding D, Macklis JD, Neubacher U, Funke K, Worgotter F
Selective elimination of corticogeniculate feedback abolishes the electroencephalogram dependence of primary visual cortical receptive fields and reduces their spatial specificity.
J Neurosci. 2003 Aug 6;23(18):7021-33.

Arlotta P, Magavi SS, Macklis JD
Induction of adult neurogenesis: molecular manipulation of neural precursors in situ.
Ann N Y Acad Sci. 2003 Jun;9 229-36.

Worgotter F, Eyding D, Macklis JD, Funke K
The influence of the corticothalamic projection on responses in thalamus and cortex.
Philos Trans R Soc Lond B Biol Sci. 2002 Dec 29;357(1428):1823-34.

Arlotta P, Magavi SS, Macklis JD
Molecular manipulation of neural precursors in situ: induction of adult cortical neurogenesis.
Exp Gerontol. 2003 Jan-Feb;38(1-2):173-82.

Fricker-Gates RA, Shin JJ, Tai CC, Catapano LA, Macklis JD
Late-stage immature neocortical neurons reconstruct interhemispheric connections and form synaptic contacts with increased efficiency in adult mouse cortex undergoing targeted neurodegeneration.
J Neurosci. 2002 May 15;22(10):4045-56.

Catapano LA, Magavi SS, Macklis JD
Neuroanatomical tracing of neuronal projections with Fluoro-Gold.
Methods Mol Biol. 2002;1 299-304.

Magavi SS, Macklis JD
No Immunocytochemical analysis of neuronal differentiation.
Methods Mol Biol. 2002;1 291-7.

Magavi SS, Macklis JD
No Identification of newborn cells by BrdU labeling and immunocytochemistry in vivo.
Methods Mol Biol. 2002;1 283-90.

Magavi SS, Macklis JD
Induction of neuronal type-specific neurogenesis in the cerebral cortex of adult mice: manipulation of neural precursors in situ.
Brain Res Dev Brain Res. 2002 Mar 31;134(1-2):57-76.

Magavi SS, Macklis JD
Manipulation of neural precursors in situ: induction of neurogenesis in the neocortex of adult mice.
Neuropsychopharmacology. 2001 Dec;25(6):816-35.

Catapano LA, Arnold MW, Perez FA, Macklis JD
Specific neurotrophic factors support the survival of cortical projection neurons at distinct stages of development.
J Neurosci. 2001 Nov 15;21(22):8863-72.
 
Macklis JD
Neurobiology: New memories from new neurons.
Nature. 2001 Mar 15;410(6826):314-5, 317.
 
Gates MA, Fricker-Gates RA, Macklis JD
Reconstruction of cortical circuitry.
Prog Brain Res. 2000;1 115-56.

Shin JJ, Fricker-Gates RA, Perez FA, Leavitt BR, Zurakowski D, Macklis JD
Transplanted neuroblasts differentiate appropriately into projection neurons with correct neurotransmitter and receptor phenotype in neocortex undergoing targeted projection neuron degeneration.
J Neurosci. 2000 Oct 1;20(19):7404-16.

Magavi SS, Leavitt BR, Macklis JD
Induction of neurogenesis in the neocortex of adult mice.
Nature. 2000 Jun 22;405(6789):951-5.

Gates MA, Tai CC, Macklis JD
Neocortical neurons lacking the protein-tyrosine kinase B receptor display abnormal differentiation and process elongation in vitro and in vivo.
Neuroscience. 2000;98(3):437-47.

Scharff C, Kirn JR, Grossman M, Macklis JD, Nottebohm F
Targeted neuronal death affects neuronal replacement and vocal behavior in adult songbirds.
Neuron. 2000 Feb;25(2):481-92.

Catapano LA, Sheen VL, Leavitt BR, Macklis JD
Differentiation of transplanted neural precursors varies regionally in adults striatum.
Neuroreport. 1999 Dec 16;10(18):3971-7.

Sheen VL, Arnold MW, Wang Y, Macklis JD
Neural precursor differentiation following transplantation into neocortex is dependent on intrinsic developmental state and receptor competence.
Exp Neurol. 1999 Jul;158(1):47-62.

Leavitt BR, Hernit-Grant CS, Macklis JD
Mature astrocytes transform into transitional radial glia within adult mouse neocortex that supports directed migration of transplanted immature neurons.
Exp Neurol. 1999 May;157(1):43-57.

Lanier LM, Gates MA, Witke W, Menzies AS, Wehman AM, Macklis JD, Kwiatkowski D, Soriano P, Gertler FB
Mena is required for neurulation and commissure formation.
Neuron. 1999 Feb;22(2):313-25.

Wang Y, Sheen VL, Macklis JD
Cortical interneurons upregulate neurotrophins in vivo in response to targeted apoptotic degeneration of neighboring pyramidal neurons.
Exp Neurol. 1998 Dec;154(2):389-402.

Snyder EY, Yoon C, Flax JD, Macklis JD
Free in PMC Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex.
Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11663-8.

Hernit-Grant CS, Macklis JD
Embryonic neurons transplanted to regions of targeted photolytic cell death in adult mouse somatosensory cortex re-form specific callosal projections.
Exp Neurol. 1996 May;139(1):131-42.

Sheen VL, Macklis JD
Targeted neocortical cell death in adult mice guides migration and differentiation of transplanted embryonic neurons.
J Neurosci. 1995 Dec;15(12):8378-92.

Snyder EY, Macklis JD
Multipotent neural progenitor or stem-like cells may be uniquely suited for therapy for some neurodegenerative conditions.
Clin Neurosci. 1995-96;3(5):310-6.

Sheen VL, Macklis JD
Apoptotic mechanisms in targeted neuronal cell death by chromophore-activated photolysis.
Exp Neurol. 1994 Nov;130(1):67-81.

Macklis JD.
Transplanted neocortical neurons migrate selectively into regions of neuronal degeneration produced by chromophore-targeted laser photolysis.
J Neurosci. 1993 Sep;13(9):3848-63.

Madison RD, Macklis JD
Noninvasively induced degeneration of neocortical pyramidal neurons in vivo: selective targeting by laser activation of retrogradely transported photolytic chromophore.
Exp Neurol. 1993 Jun;121(2):153-9.

Sheen VL, Dreyer EB, Macklis JD
Calcium-mediated neuronal degeneration following singlet oxygen production.
Neuroreport. 1992 Aug;3(8):705-8.

Macklis RM, Macklis JD
Historical and phrenologic reflections on the nonmotor functions of the cerebellum: love under the tent?
Neurology. 1992 Apr;42(4):928-32.

Liu GT, Carrazana EJ, Macklis JD, Mikati MA
Delayed oculogyric crises associated with striatocapsular infarction.
J Clin Neuroophthalmol. 1991 Sep;11(3):198-201.

Macklis JD, Madison RD
Neuroblastoma grafts are noninvasively removed within mouse neocortex by selective laser activation of intracellular photolytic chromophore.
J Neurosci. 1991 Jul;11(7):2055-62.

Macklis JD, Quattrochi JJ
Restricted diffusion and stability of carbachol-fluorescent nanospheres in-vivo.
Neuroreport. 1991 May;2(5):247-50.

Madison R, Macklis JD, Thies C
Latex nanosphere delivery system (LNDS): novel nanometer-sized carriers of fluorescent dyes and active agents selectively target neuronal subpopulations via uptake and retrograde transport.
Brain Res. 1990 Jul 2;522(1):90-8.

Macklis JD, Madison RD
Progressive incorporation of propidium iodide in cultured mouse neurons correlates with declining electrophysiological status: a fluorescence scale of membrane integrity.
J Neurosci Methods. 1990 Jan;31(1):43-6.

Quattrochi JJ, Mamelak AN, Madison RD, Macklis JD, Hobson JA
Mapping neuronal inputs to REM sleep induction sites with carbachol-fluorescent microspheres.
Science. 1989 Sep 1;245(4921):984-6.

Schick RM, Jolesz F, Barnes PD, Macklis JD
MR diagnosis of dural venous sinus thrombosis complicating L-asparaginase therapy.
Comput Med Imaging Graph. 1989 Jul-Aug;13(4):319-27.

Madison RD, Macklis JD, Frosch MP
Non-invasive laser microsurgery selectively damages populations of labeled mouse neurons: dependence on incident laser dose and absorption.
Brain Res. 1988 Mar 29;445(1):101-10.

Brasier AR, Macklis JD, Vaughan D, Warner L, Kirshenbaum JM
Myopericarditis as an initial presentation of meningococcemia. Unusual manifestation of infection with serotype W135.
Am J Med. 1987 Mar 23;82(3 Spec No):641-4.

Macklis JD, Madison R
Unfocused laser illumination kills dye-targeted mouse neurons by selective photothermolysis.
Brain Res. 1985 Dec 16;359(1-2):158-65.

Macklis JD, Sidman RL, Shine HD
Cross-linked collagen surface for cell culture that is stable, uniform, and optically superior to conventional surfaces.
In Vitro Cell Dev Biol. 1985 Mar;21(3 Pt 1):189-94.

Macklis JD, Ketterer FD, Cravalho EG
Temperature dependence of the microwave properties of aqueous solutions of ethylene glycol between +15 degrees C and -70 degrees C.
Cryobiology. 1979 Jun;16(3):272-86.

Macklis JD, Ketterer FD
Microwave properties of cryoprotectants.
Cryobiology. 1978 Dec;15(6):627-35.